Cincinnati Bengals quarterback Joe Burrow scrambles up the middle for a 20-yard run against the San Francisco 49ers.

Led by a standout performance from Brock Purdy, the San Francisco 49ers held off a late comeback attempt from Jayden Daniels and the Washington Commanders for a 23-17 victory at home.

The San Francisco 49ers face the Arizona Cardinals in Week 3. Follow live score updates, highlights, injury news, key plays and instant analysis.

Seattle Seahawks defensive tackle Byron Murphy II brings down San Francisco 49ers quarterback Brock Purdy for the sack during Sunday's Week 5 divisional matchup at Lumen Field. Seattle Seahawks running back Emanuel Wilson rushes for a 2-yard touchdown in the first half against the San Francisco 49ers in Week 5.

SANTA CLARA, Calif. (AP) — Brock Purdy and the San Francisco 49ers have been in peak form early this season. The Niners lead the league in yards per play and success rate, have limited negative plays and rank second in the league in scoring to fuel a 3-0 start.

Purdy and McCaffrey keep the undefeated streak alive, but mounting injuries and costly penalties threaten San Francisco’s dominance as they prepare for a physical clash in Atlanta. Some of the 49ers' flaws were exposed against the Commanders on Monday night.

The Seahawks and 49ers play in a pivotal NFC West showdown. Follow along with our live score updates, highlights, injury news and instant analysis!