Bone tissue engineering (BTE) has emerged as a critical solution for repairing large bone defects caused by trauma, infection ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing ...

Riley Children’s used deceased donor stem cells to treat a teen with leukemia, a method that may reduce wait times and expand ...

While research has uncovered many details about how blood cells function within bone marrow, the work of other cells existing in that space has remained a relative mystery. Now, researchers from the ...

Bones continue to grow robustly through early postnatal to juvenile stages. Remarkably, the length of the long bones increases by ~3 to 4 times during these stages in mice 1. At the same time, bone ...

Osteoblasts are specialized bone cells responsible for building and regenerating bone tissue. Researchers at Leipzig University have shown that a specific receptor plays a key role in the strength of ...

Bone fractures represent a significant global healthcare burden. Although fractures typically heal on their own, some fail to regenerate properly, leading to nonunion, a condition that causes ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled by Angptl7. They found that these cells are crucial for bone fracture repair ...