Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such as reprogramming a stem cell into a neuron or generating a protein that ...

A gene called SDR42E1 has been identified as a key player in how our bodies absorb and process vitamin D. Researchers found that disabling this gene in colorectal cancer cells not only crippled their ...

Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better drugs for this psychiatric disorder. To test this hypothesis, Girgenti and his ...

The animal kingdom contains a vast array of animals capability of remarkable regenerative abilities, but known are quite as adept at this healing task than sea-swelling Cnidarians, such as hydra, ...

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S., and ...