New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...

Most cancers originate from genetic abnormalities, specifically the accumulation of somatic mutations. These mutations accumulate in normal cells in all organs of healthy individuals and are driven by ...

Synonymous mutations are generally considered neutral, while their roles in the human genome remain largely unexplored. Here we use the PEmax system to create a library of 297,900 engineered ...

Using next generation gene sequencing techniques, cancer researchers at UT Southwestern Medical Center have identified more than 3,000 new mutations involved in certain kidney cancers, findings that ...