A high platelet count indicates too many of the small cells (platelets) that help form blood clots. This can cause dangerous clots and bleeding. Also called thrombocytosis or thrombocythemia, ...

"These patients [with extreme thrombocytosis] had improved overall survival and lower bleeding risk compared to those with normal or low platelet counts at the time of diagnosis." — Marko Lucijanic, ...

Persistent thrombocytosis in ET increases arterial/venous thrombosis risk and, at extreme counts, acquired platelet dysfunction with hemorrhage, making risk stratification and symptom surveillance ...

Patients with ET experience diagnostic delays, averaging 26.5 months from the first elevated platelet count to diagnosis, indicating potential underestimation of the disease's burden. The study ...