Natural product libraries enable the discovery of bioactive compounds through diverse screening workflows. Inherent ...

Natural products have long been a treasure trove for drug discovery, with their diverse bioactivity and historical use in traditional medicine inspiring numerous clinical advancements. A recent review ...

(A) A comprehensive analysis of caffeine binding to one of the spike proteins; (B, C) Caffeine interacts with critical amino acids in the SARS-CoV-2 S protein’s receptor-binding domain (RBD), ...

The results of research led by scientists at Harvard Medical School suggest that a natural product antibiotic first isolated back in the 1940s may be effective against potentially lethal, multidrug ...

BOULDER, Colo.--(BUSINESS WIRE)--Enveda Biosciences, a biotechnology company discovering new medicines from natural sources, released the details of one of its foundational AI models, MS2Mol, in a pre ...

Myxobacteria constitute a unique group of Gram‐negative, soil‐dwelling bacteria noted for their complex, cooperative lifestyles and remarkable capacity to produce an array of secondary metabolites.

Marine organisms produce a wide variety of primary and secondary metabolites with unique scaffolds that are biologically active. Manzamines are marine-derived polycyclic alkaloids. Approximately 100 ...

Malaria remains a major global health burden, and the continued emergence of resistance to frontline therapies, including artemisinin-based combination ...

Nature has been the traditional source for organic chemical compounds used in medicine. For over 3,000 years, early societies recognized that their immediate environments were a rich source of plants ...

Capturing compounds directly from the organisms’ natural habitats could help avoid this bottleneck, one that has limited product discovery to what microbes can be made to produce in the lab. “When we ...