Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

In a landmark achievement in biological imaging, researchers at Biohub and the University of California, Berkeley today ...

In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today announced the successful demonstration of the laser phase plate, a novel device ...

Quantitative phase microscopy (QPM) has emerged as a revolutionary tool, enabling label-free imaging of biological specimens without the need for disruptive dyes or stains 1. This technique preserves ...

Quantitative phase imaging (QPI) applied to holographic microscopy harnesses coherent light interference to record both intensity and phase information, enabling label-free visualisation of ...

A new microscope method reveals details that were difficult to see before, helping researchers study proteins, cells, and ...

Berkeley Lab and UC Berkeley physicists' new technique offers detailed images of the small molecules and cell structures that ...

Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.

Researchers have introduced a solution to the problem of light-sheet fluorescence microscopy: novel illumination beams designed based on deep learning using a trainable phase mask. Their study ...

(A) When a traditional Gaussian beam is used, diffraction causes the illumination beam to widen at the edges. (B) Joint optimization scheme. A network predicts the positions of beads in the focal ...