A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics. Many ...

A new study has found an association between elevated levels of a protein, known as Miro1, in skeletal muscle and type 2 ...

The human genome comprises both canonical protein-coding genes and a vast number of non-canonical coding regions, yet the translation products of the latter remain largely underexplored. Now, the ...

A peer-reviewed review examines protein acylation as a link among cancer metabolism, tumor plasticity, therapeutic resistance ...

Beginners often hone their skills on easy-to-crystallize proteins such as lysozyme (top), structural biochemist Saacnicteh ...

In the ERC project HelixMold, a team from TU Graz developed a method for the computer-based design of artificial proteins, with a focus on custom biocatalysts for pharmaceutical applications or the ...

Researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall. McMaster ...

SynthID Bio, Google DeepMind's protein watermarking system published in Nature on September 30, embeds hidden provenance signatures in AI-designed proteins without degrading binding function. Wet-lab ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...

A UC Riverside team funded by FRAXA will test engineered proteins designed to cross the blood-brain barrier and normalize brain activity in Fragile X syndrome mice.

Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases. In two new ...