Although diverse signaling cascades require the coordinated regulation of heterotrimeric G proteins and small GTPases, these connections remain poorly understood. We present the crystal structure of ...
The sustained presence in the nucleus of the protein known as Rac1 produces changes in nuclear morphology that are important in several biological processes, including malignant cancer. This is the ...
The kidney's proximal tubule reabsorbs water, glucose, ions and other small molecules from the urine and thus maintains the body's supply of these essential constituents. The tubule can be easily ...
A promising therapeutic target has been discovered for improving lung function in infants. The study shows that a protein called Rac1 is critical for the proper development of mammalian lung. A study ...
A new study by researchers at Karolinska Institutet shows that the local activity of the signaling molecule Rac1 controls cycles of microscopic protrusions and retractions of the cell membrane. The ...
A study by researchers from The Saban Research Institute of Children's Hospital Los Angeles reveals a promising therapeutic target for improving lung function in infants. Their study, now published ...
The prolonged presence of Rac1 in the nucleus leads to changes in nuclear morphology that are important in cell migration. The existence of nuclear Rac1 has been known for a few years, but mystery has ...
A study by researchers from The Saban Research Institute of Children's Hospital Los Angeles reveals a promising therapeutic target for improving lung function in infants. Their study, now published ...
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