Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, irreversible processes, such as transcribing DNA into RNA, to keep life going.
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from ...
A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene ...
In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...
A principle of DNA synthesis that has dominated biology textbooks for decades could be upended. An enzyme has been discovered ...
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Cracking the code of chromatin and gene control
From memory formation to disease prevention, scientists are uncovering how chromatin structure, enzyme evolution, and epigenetic regulators orchestrate gene activity. Recent breakthroughs reveal how ...
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in gene activity between male and female brains. This may help explain why some ...
In a new study published in Genes & Development, research led by Dr. Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for ...
A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in ...
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