RMD Open

Whole-blood coagulation and platelet dynamics identify differential prothrombotic states in patients with rheumatoid arthritis treated with JAK or TNF-É‘ inhibitors

Background Rheumatoid arthritis (RA) is associated with inflammation-driven hypercoagulability and increased venous ...
RMD Open

How multi-omic technologies can help define paediatric undifferentiated systemic autoinflammatory diseases: the experience of the European PerSAIDs consortium

Systemic AutoInflammatory Diseases (SAIDs) are rare conditions characterised by impaired control of inflammatory and innate ...
RMD Open

Ultrasound-based withdrawal of biologics in rheumatoid arthritis (RA-BioStop)

Objective To test whether ultrasonography of patients with rheumatoid arthritis (RA) in the American College of ...
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Real-world safety assessment of avacopan in patients with antineutrophil cytoplasmic antibody-associated vasculitis

Objective Postmarketing safety data of avacopan, the first Food and Drug Administration (FDA) approved drug in a decade for antineutrophil cytoplasmic antibody-associated vasculitis (AAV), are ...
rmdopen.bmj

Long-term outcomes in patients with polyarticular juvenile idiopathic arthritis receiving adalimumab with or without methotrexate

Objectives Long-term safety and efficacy of adalimumab among patients with juvenile idiopathic arthritis (JIA) was evaluated through 6 years of treatment. Methods Children aged 4–17 years with ...
rmdopen.bmj

Bilateral swelling of the salivary glands and sicca symptoms: an unusual differential diagnosis—Kimura’s disease, a rare allergic condition with a high IgE serum level—a ...

A 68-year-old woman presented with bilateral swelling of the salivary glands, sicca symptoms of eyes and mouth, itching, fatigue and weight gain of about 5 kg in the last 2–3 years. As part of a ...
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Systematic literature review informing the 2022 update of the EULAR recommendations for the management of ANCA-associated vasculitis (AAV): part 1—treatment of granulomatosis ...

Objective To summarise and update evidence to inform the 2022 update of the EULAR recommendations for the management of antineutrophil cytoplasm antibody-associated vasculitis (AAV). Methods A ...
rmdopen.bmj

The wide range of opportunities for large language models such as ChatGPT in rheumatology

Now that’s what you call technical disruption: When has a technical invention ever spread so quickly since the introduction of the iPhone in 2007? One million users in 5 days… It’s like the world has ...
rmdopen.bmj

Clinical, radiological and pathological features of anti-MDA5 antibody-associated interstitial lung disease

Introduction To investigate the clinical, radiographic and pathological features of interstitial lung disease (ILD) in patients with anti-melanoma differentiation-associated gene 5 antibody-positive ...
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Prolonged COVID-19 symptom duration in people with systemic autoimmune rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey

Objective We investigated prolonged COVID-19 symptom duration, defined as lasting 28 days or longer, among people with systemic autoimmune rheumatic diseases (SARDs). Methods We analysed data from the ...
rmdopen.bmj

Inflammation, bone loss and fracture risk in spondyloarthritis

Osteoporosis (ie, low bone mineral density) is common in ankylosing spondylitis, related to both systemic inflammation and decreased mobility. Vertebral fracture risk is increased; acute back pain in ...
rmdopen.bmj

Repair of joint damage in patients with rheumatoid arthritis does not relate to previous suppression of inflammation: a subanalysis after 8 years treat-to-target in the BeSt-trial

Objectives To investigate whether repair of erosions and joint space narrowing (JSN) in rheumatoid arthritis (RA) occurs and whether clinical variables predict this. Methods Eight-year follow-up data ...