Europe PMC

Two complete telomere-to-telomere Medicago genomes reveal the landscape and evolution of centromeres.

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Europe PMC

Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.

Abstract While exploring strategies to control blood glucose concentrations in diabetes, we identified so-called molecular glues D223 and D927 that promote glucose uptake in the absence of insulin.
Europe PMC

Comparison and trend analysis of cancer incidence in China and globally in 2022

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Europe PMC

Characterization of the Biological Effect Mediated by Mycobacterial Kinase PknG on Protein Phosphorylation and Acetylation

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Europe PMC

Unraveling the SOX11-IGF2 signaling axis in early lung development: implications for lung disease.

The essential function of SOX11 in directing mammalian organogenesis is well-established. Nevertheless, the intricate signaling network it orchestrates, especially during early lung development, ...
Europe PMC

Engineered odorant receptors illuminate the basis of odour discrimination.

Europe PMC is an archive of life sciences journal literature.
Europe PMC

Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.

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Europe PMC

Granulosa cells alone, without theca cells, can mediate LH-induced oocyte meiotic resumption.

Signaling in the granulosa cells of mammalian ovarian follicles is necessary for maintaining prophase arrest in the oocyte and for mediating the resumption of meiosis in response to luteinizing ...
Europe PMC

A Review of the Industrial Importance, Common Bacterial Diseases, and Zoonotic Risks of Freshwater Aquarium Fish.

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Europe PMC

Introduction of tert-butyldiphenylsilyl (TBDPS) group

Nishihara S, Angata K, Aoki-Kinoshita KF, et al., editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and ...
Europe PMC

A preparation method for mRNA-LNPs with improved properties.

The properties of mRNA lipid nanoparticles (mRNA-LNPs), including size, empty particles, morphology, storage stability, and transfection potency, are critically dependent on the preparation methods.
Europe PMC

Scalable Synthesis and Electrocatalytic Performance of Highly Fluorinated Covalent Organic Frameworks for Oxygen Reduction.

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